Watermelon (Citrullus lanatus (Thunb.) Matsum. and Nakai) Juice Modulates Oxidative Damage Induced by Low Dose X-Ray in Mice

نویسندگان

  • Mohd Khairul Amran Mohammad
  • Muhamad Idham Mohamed
  • Ainul Mardhiyah Zakaria
  • Hairil Rashmizal Abdul Razak
  • Wan Mazlina Md Saad
چکیده

Watermelon is a natural product that contains high level of antioxidants and may prevent oxidative damage in tissues due to free radical generation following an exposure to ionizing radiation. The present study aimed to investigate the radioprotective effects of watermelon (Citrullus lanatus (Thunb.) Matsum. and Nakai) juice against oxidative damage induced by low dose X-ray exposure in mice. Twelve adult male ICR mice were randomly divided into two groups consisting of radiation (Rx) and supplementation (Tx) groups. Rx received filtered tap water, while Tx was supplemented with 50% (v/v) watermelon juice for 28 days ad libitum prior to total body irradiation by 100 μGy X-ray on day 29. Brain, lung, and liver tissues were assessed for the levels of malondialdehyde (MDA), apurinic/apyrimidinic (AP) sites, glutathione (GSH), and superoxide dismutase (SOD) inhibition activities. Results showed significant reduction of MDA levels and AP sites formation of Tx compared to Rx (P < 0.05). Mice supplemented with 50% watermelon juice restore the intracellular antioxidant activities by significantly increased SOD inhibition activities and GSH levels compared to Rx. These findings may postulate that supplementation of 50% watermelon (Citrullus lanatus (Thunb.) Matsum. and Nakai) juice could modulate oxidative damage induced by low dose X-ray exposure.

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

تـأثیر کم آبیاری بر عملکرد، اجزاء عملکرد و تولید بذر سه رقم هندوانه (Citrullus lanatus (Thunb) Matsum and Nakai)

A two-year study (2005 - 2006) was carried out to explore the effect of deficit irrigation treatments according to evaporation from a class A basin, including ET= 1 (T1), ET = 0.75 (T2), and ET = 0.5 (T3), on yield, yield components and seed yield of three varieties of watermelon (Charleston Gray, Sugar Baby and Crimson Suite) in the Varamin Agricultural Research Center of Iran. A randomized co...

متن کامل

Lures and Traps

Cucurbitacin E glycoside, extracted from a bitter mutant of Hawkesbury watermelon [Citrullus lanatus (Thunb.) Matsum. & Nakai (Syn. Citrullus vulgaris Schrad)] is the active ingredient of a feeding stimulant for the corn rootworm complex. It is the primary component of a water-soluble bait that can be combined with toxins for adult diabroticite control. Studies were conducted using phloxine B (...

متن کامل

Qualitative inheritance of rind pattern and flesh color in watermelon.

Watermelon [Citrullus lanatus (Thunb.) Matsum. & Nakai var. lanatus] is a diverse species, with fruits of different sizes, shapes, rind patterns, and flesh colors. This study measured the inheritance of novel rind phenotypes and verified the genetics of white, red, salmon yellow, and canary yellow flesh colors. For each of the 11 crosses, six generations (P(a)S1, P(b)S1, F1, F2, BC1P(a), and BC...

متن کامل

Characterization of Watermelon ( Citrullus lanatus var . citroides ) Germplasm for Resistance to Root - knot Nematodes

Root-knot nematodes (Meloidogyne spp.) cause extensive damage to watermelon ICitrz,llus lanatus (Thunb.) Matsum. & Nakai var. lanatusl, and resistance to rootknot nematodes has not been identified in any watermelon cultivar. Twenty-six U.S. Plant Introductions (Pis) of Citrullus lanatus (Thunb.) Matsum. & Nakai var. citroides (L. H. Bailey) Mansf., one P1 of C. lanatus var. lanatus, and three P...

متن کامل

Discovery of second gene for solid dark green versus light green rind pattern in watermelon.

The watermelon (Citrullus lanatus (Thunb.) Matsum. & Nakai var. lanatus) has high variability for fruit size, shape, rind pattern, and flesh color. This study was designed to measure the qualitative inheritance of rind phenotypes (solid dark green vs. light green). For each of the 2 families, "Mountain Hoosier" × "Minilee" and "Early Arizona" × "Minilee," 6 generations (P(a)S(1), P(b)S(1), F(1)...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:

دوره 2014  شماره 

صفحات  -

تاریخ انتشار 2014